Barbara BOHLE, PhD

bohle

Head of the Department of Pathophysiology and Allergy Research, Medical University of Vienna
Head of the Allergy Research group at the Department of Pathophysiology and Allergy Research

Education:
PhD, University Prof. of Cellular Allergology

Research Interests:

• Pathophysiology of IgE-mediated allergy
• Characterization and modification of allergens
• Prevention and therapy of allergic diseases

Biography

Barbara Bohle has studied "Food- and Biotechnology" at the University of Natural Resources and Applied Life Sciences in Vienna after working as a Medical Technical Assistant in the team of Prof. Dietrich Kraft at the Institute of Experimental Pathology, University of Vienna, Austria, for 5 years. In 2000 she received her PhD and in 2002 the Venia docendi in Immunology. Since then she leads the research group “Allergy Research” at the Department of Pathophysiology and Allergy Research at the Medical University of Vienna. In 2010 she was appointed a full professor for Cellular Allergology. Since 2011 she is the Head of the Institute of Pathophysiology and Allergy Research and the Division of Experimental Allergology. From 2007-2015 she led the Christian Doppler Laboratory for Immunomodulation.
The main focus of her scientific work is the elucidation of the immune mechanisms underlying the induction, maintenance and therapy of IgE-mediated allergy. Her scientific work markedly contributed to the understanding of the pathophysiology of pollen-related food allergy and was awarded with prestigious national and international prizes. She is the author of >170 peer-reviewed scientific papers published in highly ranked journals in the field of allergy and immunology. Up to now, 8 PhD theses, 12 diploma/master theses and 11 bachelor theses were completed under her supervision. More information on her current team at https://www.meduniwien.ac.at/hp/ipa/forschung/forschungsgruppen/bohle-barbara-allergy-research/

Proposed PhD research projects:
Prevention of birch pollen and birch-related food allergy

Selected publications:

  1. Sánchez Acosta, G., T. Kinaciyan, C. Kitzmüller, C. Möbs, W. Pfützner, and B. Bohle. 2020. IgE-blocking antibodies following SLIT with recombinant Mal d 1 accord with improved apple allergy. J Allergy and Clin Immunol, doi: 10.1016/j.jaci.2020.03.015, online ahead of print

  2. Polak, D., C. Hafner, P. Briza, C. Kitzmüller, A. Elbe-Bürger, N. Samadi, M. Gschwandtner, W. Pfützner, G.J. Zlabinger, B. Jahn-Schmid, and B. Bohle. 2019. A novel role for neutrophils in IgE-mediated allergy: evidence for antigen-presentation in late-phase reactions. J Allergy Clin Immunol. 143:1143-1152.e4. PMID: 29920351

  3. Zulehner, N., B. Nagl, P. Briza, A. Roulias, B. Ballmer-Weber, G. J. Zlabinger, F. Ferreira, and B. Bohle. 2017. Characterization of the T cell response to Dau c 1, the Bet v 1-homolog in carrot. Allergy. 72:244-251. PMID: 27222434

  4. Kollmann, D., B. Nagl, C. Ebner, W. Emminger, S. Wöhrl, C. Kitzmüller, S. Vrtala, A. Mangold, H.J. Ankersmit, and B. Bohle. 2017. The quantity and quality of α-gal-specific antibodies differ in individuals with and without delayed red meat allergy. Allergy. 72:266-273. PMID: 27261450

Other Publications extlink